Homework NAME_____________________________________

Microbiology

DUE November 12, 2007 AT CLASS TIME

Go to www.emedicine.com, sign up to use their web site – I suggest you DO NOT opt to receive their free e-mail updates (you must UN-check all the boxes). Search for “Escherichia.”

After you sign up, you may have to search again. Search “Escherichia”; find “Medicine, Ob/Gyn, Psychiatry, and Surgery, Infectious Diseases” If your search says “topic not available at this time” just search again and it will come up.

1. What are the most common diseases that this bacteria causes?

2. What is the mortality rate of babies with Escherichia neonatal sepsis?

3. What do the following stand for, what diseases do they cause, and where do they colonize?

a. ETEC

b. EPEC

c. EIEC

d. EHEC

e. EAggEC

f. EAEC

4. What is the most common site of infection for E. coli?

Search “Klebsiella” find “Medicine, Ob/Gyn, Psychiatry, and Surgery, Infectious Diseases” = first hit

1. To what family does Klebsiella belong?

2. Who is this tribe named after?

3. How many different types of capsular antigens are there? How many different types of lipopolysaccharide antigens are there?

4. What are the three most medically significant species of Klebsiella?

5. Under “Pathophysiology”

a. Describe the host defense mechanisms.

b. What characteristics of Klebsiella enable it to evade the innate (non-specific, 1^st and 2^nd lines of defense) host defenses?